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International Journal of Health and Rehabilitation Sciences

International Journal of Health and Rehabilitation Sciences
ISSN (online) : 2278-9030
ISSN (Print) : 2278-9014
ISSUES : 4/year
PUBLISHER : Rehabilitation Without Borders

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Review Article 


Safety and Efficacy of Pharmacological Management of Agitation in Alzheimer’s Dementia - A Review

Anjali N Kalore, Dhananjay Medappa, Eukesh Ranjit, Sandeep S Nayak.

Cited by (2)

Abstract
Agitation is a common and distressful symptom in Alzheimer’s dementia. Pharmacological treatment is frequently needed when symptoms are moderate to severe. Basic etiology and pathogenesis of agitation is not well understood and this makes targeted pharmacotherapy challenging. Many drugs have been tried but FDA has not approved any drug for treatment and there is lack of consensus. We review the principles, indications and current Level I evidence on the safety and efficacy of various drugs used for treatment of agitation in Alzheimer’s Dementia. We find that newer drugs like citalopram and prazosin have greater efficacy and are better tolerated than antipsychotic medications.

Key words: Safety, Efficacy, Pharmacological Management, Agitation, Alzheimer’s Dementia


 
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This Article Cited By the following articles

A population pharmacokinetic model for R- and S-citalopram and desmethylcitalopram in Alzheimer’s disease patients with agitation
J Pharmacokinet Pharmacodyn 2016; 43(1): 99.

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A population pharmacokinetic model for R- and S-citalopram and desmethylcitalopram in Alzheimer’s disease patients with agitation
J Pharmacokinet Pharmacodyn 2015; (): .

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How to Cite this Article
Pubmed Style

Anjali N Kalore, Dhananjay Medappa, Eukesh Ranjit, Sandeep S Nayak. Safety and Efficacy of Pharmacological Management of Agitation in Alzheimer’s Dementia - A Review. IJHRS. 2015; 4(1): 65-72. doi:10.5455/ijhrs.000000073

Web Style

Anjali N Kalore, Dhananjay Medappa, Eukesh Ranjit, Sandeep S Nayak. Safety and Efficacy of Pharmacological Management of Agitation in Alzheimer’s Dementia - A Review. https://www.ijhrs.org/?mno=187847 [Access: August 12, 2022]. doi:10.5455/ijhrs.000000073

AMA (American Medical Association) Style

Anjali N Kalore, Dhananjay Medappa, Eukesh Ranjit, Sandeep S Nayak. Safety and Efficacy of Pharmacological Management of Agitation in Alzheimer’s Dementia - A Review. IJHRS. 2015; 4(1): 65-72. doi:10.5455/ijhrs.000000073


Vancouver/ICMJE Style

Anjali N Kalore, Dhananjay Medappa, Eukesh Ranjit, Sandeep S Nayak. Safety and Efficacy of Pharmacological Management of Agitation in Alzheimer’s Dementia - A Review. IJHRS. (2015), [cited August 12, 2022]; 4(1): 65-72. doi:10.5455/ijhrs.000000073


Harvard Style

Anjali N Kalore, Dhananjay Medappa, Eukesh Ranjit, Sandeep S Nayak (2015) Safety and Efficacy of Pharmacological Management of Agitation in Alzheimer’s Dementia - A Review. IJHRS, 4 (1), 65-72. doi:10.5455/ijhrs.000000073


Turabian Style

Anjali N Kalore, Dhananjay Medappa, Eukesh Ranjit, Sandeep S Nayak. 2015. Safety and Efficacy of Pharmacological Management of Agitation in Alzheimer’s Dementia - A Review. International Journal of Health and Rehabilitation Sciences (IJHRS), 4 (1), 65-72. doi:10.5455/ijhrs.000000073


Chicago Style

Anjali N Kalore, Dhananjay Medappa, Eukesh Ranjit, Sandeep S Nayak. "Safety and Efficacy of Pharmacological Management of Agitation in Alzheimer’s Dementia - A Review." International Journal of Health and Rehabilitation Sciences (IJHRS) 4 (2015), 65-72. doi:10.5455/ijhrs.000000073


MLA (The Modern Language Association) Style

Anjali N Kalore, Dhananjay Medappa, Eukesh Ranjit, Sandeep S Nayak. "Safety and Efficacy of Pharmacological Management of Agitation in Alzheimer’s Dementia - A Review." International Journal of Health and Rehabilitation Sciences (IJHRS) 4.1 (2015), 65-72. Print. doi:10.5455/ijhrs.000000073


APA (American Psychological Association) Style

Anjali N Kalore, Dhananjay Medappa, Eukesh Ranjit, Sandeep S Nayak (2015) Safety and Efficacy of Pharmacological Management of Agitation in Alzheimer’s Dementia - A Review. International Journal of Health and Rehabilitation Sciences (IJHRS), 4 (1), 65-72. doi:10.5455/ijhrs.000000073

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